NC State gurus find ‘Goldilocks’ of DNA self-assembly, look to improve drug-delivery vehicles

We’re guessing that most Wolfpackers in the greater Raleigh area are in full-on tailgate mode right now, but aside from laying a beating on the Seminoles this evening, NC State faithful are also trumpeting a new DNA discovery that could one day make it easy to get vital drugs to hard-to-reach places within you. Researchers from the university have purportedly discovered the ‘Goldilocks’ of DNA self-assembly, which holds promise for technologies ranging from drug delivery to molecular sensors. The concept, known as DNA-assisted self-assembly, has been vastly improved by using “computer simulations of DNA strands to identify the optimal length of a DNA strand for self-assembly.” You see, perfection occurs when strands aren’t long enough to intertwine with each other, yet not short enough to simply fold over on each other. We know, it’s a lot to wrap your brain around with half a hot dog shoved in your mouth, but hit the video after the break for a… shall we say, more visual explanation. Continue reading NC State gurus find ‘Goldilocks’ of DNA self-assembly, look to improve drug-delivery vehicles NC State gurus find ‘Goldilocks’ of DNA self-assembly, look to improve drug-delivery vehicles originally appeared on Engadget on Thu, 28 Oct 2010 15:35:00 EDT. Please see our terms for use of feeds . Permalink

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